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  • "A comparative assessment of current and future pharmacovigilance in developed and developing countries - A case study of Ireland and Nigeria" by OLANREWAJU JIMOH

    MR OLANREWAJU JIMOHMedicine majorly constitutes the use of prescribing and administering drugs by healthcare professionals majorly the pharmacist and the medical doctors. The importance of these two professions is very paramount in fighting diseases and promoting good healthcare as well as the general well-being of humans. Also, the current drug discovery and research within the pharmaceutical industry have led to the will for the need for the safety and efficacy of drug products. The safety of the drug has been a major concern aftermarket authorization due to limited clinical trials which cannot prove the safety of the public health after consumption. Adverse drug reaction has always been a major challenge in the life of drug users and this cannot be avoided but rather can be prevented. The standard clinical trial phases include phase 1 which usually comprises a certain number of humans, mostly less than 20, and their safety with a lesser dosage of the drug, phase 2 is 50 to 100 towards the adequate dosage specifications. Phase 3 is usually carried towards a specific condition at which the drug is being produced for the effectiveness in treating a certain condition while phase 4 is conducted to identify the long term effects of the drug after the approval and enters the market. All these phases have led to pharmacovigilance activities of ADR reporting on how drug products are working after taking and the safety of the people using it.

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     Objectives:

    The thesis objectives are to compare and evaluate the factors about reporting Adverse Drug Reactions in the developed and developing countries among healthcare professionals (Medical doctors and Pharmacists) using Ireland and Nigeria as a case study.

    Methodology:

    A questionnaire survey and phone interviews for quantitative and qualitative analysis are carried out respectively within the two regions (Ireland and Nigeria). The challenges faced by medical professionals concerning ADR reporting are achieved based on their knowledge and awareness to determine an effective recommendation to help improve both regions using the comparison results and works of literature gathered.

     
    Findings:

    An Overall total of 122 respondents from both Nigeria and Ireland are received which consists of 47 respondents from Ireland (12 medical doctors and 35 pharmacists) and 75 respondents from Nigeria (32 medical doctors and 43 pharmacists) showing a response rate of 60.0% and 87.5% from 20 and 45 medical doctors and pharmacist from Ireland and response rate of 71.1% and 95.5% out of 45 respondents respectively from both medical doctors and pharmacist from Nigeria. Surprisingly, 98.0% of the correspondents which consist of 12 medical doctors and 35 pharmacists from Ireland responded to knowing how to report ADRs to compare to 71.0% from Nigeria which is quite above average consisting of 26 medical doctors and 27 pharmacists responded to knowing how ADRs is being reported. However, it shows that pharmacists had better knowledge, awareness, understanding, and experience over the medical doctors regarding ADRs reporting. However, 92.0% and 96.0% of respondents of both groups from Nigeria and Ireland respectively opted to ADR reporting being made compulsory as a professional obligation towards achieving and improving pharmacovigilance.
     
    Analysis:

    It shows that the challenges affecting ADR reporting in Nigeria are associated with the inaccessibility of ADR report forms when needed, complex reporting processes while too busy and lack of time remained the most common challenging factor among this too regions. The least common challenges reported at both regions are level of clinical trial knowledge, a concern that ADR report mighty is wrong among, fear of legal liabilities, and fear of exposure to legal liabilities from patient or drug manufacturer.

    Conclusions:

    Proper comparison and recommendation from both sides from the country shows the need for better improvement in awareness among healthcare professionals in Nigeria been the country with the highest level of challenges compare to their counterpart healthcare professionals and this could be achieved by organizing pharmacovigilance conferences, continuous education programs included in their professional courses and training to improve knowledge of ADR reporting. Establishment of ADR departments in healthcare institutions headed by ADR specialists and offering professional recognition rather than financial rewards are the sustainable recommendation to put in practice in both regions to further improve the practice of ADR reporting in Nigeria and Ireland. To wrap it up, the need for the regulatory bodies from the developing countries to work in hand with the developed countries to better improves awareness, knowledge, and improvement towards ADRs reporting system.

  • "AN ANALYSIS OF HOW COLLABORATION BETWEEN PHYSICIANS AND PHARMACISTS MIGHT FACILITATE IMPROVED HEALTHCARE IN NIGERIA" by Moyosore Osoko Oluwatoyosi

    Moyosore Oluwatoyosi OsokoInter-professional collaboration among healthcare workers impacts the delivery of healthcare, of all these professionals, physicians and pharmacist collaboration has the greatest effect on positive patient outcomes which is the goal of healthcare. All over the world there have been repeated studies into this relationship and they have shown that an excellent inter-professional collaboration between physicians and pharmacists led to positive patient outcomes. In Nigeria, the healthcare sector is not paid much attention by the government, it is under-funded, the workers are overworked and not properly remunerated and citizens also deal with poverty. Despite all these, the country can still benefit from good collaboration between physicians and pharmacists in order to deliver quality healthcare to its populace.

     

     


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     Objectives:

    The objectives of this research traversed:

    (1). Analysis of the inter-professional collaboration among healthcare professionals, specifically physicians and pharmacists in Nigeria.

    (2). Evaluating the factors that hinder this collaboration in Nigeria.

    (3). Evaluating the factors that improve this collaboration in Nigeria.

    (4). Suggesting feasible solutions that will bolster the collaboration between physicians and pharmacists in Nigeria.

    Methodology:

    The research methodology employed was a mixture of qualitative and quantitative approaches through a mixed-method questionnaire making use of the online platform, google forms. The questionnaire was devoid of bias, no personal questions were asked and there was no interference on the part of the author to the responses garnered. The qualitative approach was phenomenological centered around the daily experiences of physicians and pharmacists. The questionnaire was dispersed to physicians and pharmacists in government hospitals, primary care centers, community pharmacists and patients in these environments. Likert scales were employed in measuring the varying views on the subject. The patients were also asked their opinion of physicians, pharmacists and the quality of healthcare they receive.
     
    Findings:

    The research confirmed a finding from the literature review that in this relationship, community pharmacists are indispensable as they account for the majority of pharmacists in Nigeria. This is also important because they interact the most with patients. The research also showed a current scarcity of interactions between physicians and pharmacists which shows why this has been foreign in Nigeria's healthcare sector. Physicians and pharmacists that have interacted have had an amenable relationship, this shows that the relationship is welcome and has the capacity to improve healthcare in Nigeria. Finally, patients visit their pharmacists for the more common ailments highlighting their importance and the possibility of a good relationship when these two professionals work hand in hand.
     
    Analysis:

    This research to the best of my knowledge was the first of its kind in Nigeria. It is important because for a developing country, healthcare is an important sector that cannot be overlooked. In developed countries, inter-professional collaboration has been widely researched and confirmed to improve the healthcare of their patients and the goal of the research is to test the veracity of this knowledge in a developing country like Nigeria. This was done by gathering responses from physicians, pharmacists and patients by employing a mixed method questionnaire, seeking their opinion because it directly affects them. The result showed that this collaboration is almost non-existent in Nigeria and a lot of work needs to be done by the government, healthcare professionals, the governing bodies of these professions and even the public in order to bring this collaboration to fruition and cause good clinical outcomes.

    Conclusions:

    A major discovery of this body of work from the secondary research was that community pharmacists have a huge role to play in this relationship, findings from primary research also confirmed this. This relationship also has not been developed effectively in Nigeria, but it is welcome nonetheless. Unsurprisingly also, physicians in Nigeria do not view pharmacists as colleagues, they have little respect for this profession this is enhanced by lack of proper communication between these professionals and even the patients. The Nigerian government need to be more proactive and invest in the Nigerian healthcare system, the study of this relationship should also be introduced into the curriculum of medical and pharmacy students. Finally, there should be establishment of electronic medical records and accountable care organizations that enhances access to patient information under the strictest regulations.

  • "Challenges impacting the reporting of Adverse Drug Reactions among healthcare professionals: Improving pharmacovigilance in Nigeria." by Dr. Prosper Chibuikem Anaedu

    ProsperAn ADR is a drug response that is unintended and occurs at doses normally used in man for prophylaxis, therapy or the modification of physiological function. ADR reporting is critical in improving pharmacovigilance in Nigeria. This oversees the activities that relates to the knowledge, detection, assessment and prevention of adverse events or any drug-related issue. This research was undertaken with the purpose of identifying and exploring the challenges faced by healthcare professionals in spontaneously reporting ADRs, with the aim of improving reporting rates, promoting drug safety practices and reducing the burden of ADRs in Nigeria. Issues emanating from ADRs are highly critical because of the drug misinformation, misuse, advanced age-related physiological, biological, pharmacokinetic and pharmacodynamic changes observed. When patients suffer from ADRs, it is challenging to determine how severe the outcomes are, even when the prescribed drug benefits clearly outweigh the risks.

     

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     Objectives:

    The author explored the knowledge, attitude and experience of ADR spontaneous reporting among medical doctors and pharmacists in line with established guidelines and regulations by the relevant authorities in Nigeria. Although current spontaneous reporting practices are less than optimal, this research dissertation was aimed at articulating effective strategies that could be optimally leveraged to improve the frequency and quality of reporting while driving better positive health outcomes for patients across Nigeria. An outline of the research objectives include:

    1. To evaluate the knowledge and awareness of ADR reporting among healthcare professionals in Nigeria

    2. To assess challenges among healthcare professionals in the practice of ADR reporting in Nigeria.

    3. To make sustainable recommendations to improve ADR reporting among healthcare professionals in Nigeria.

    Methodology:

    Primary and secondary research methods were utilised by the author through the electronic dissemination of questionnaires, phone interviews and literature reviews. The secondary research was first carried out to explore relevant current literature from reputable research databases and journals on ADR reporting to determine the gaps as it pertains to the established research objectives. Attempts to fill these gaps were subsequently carried out through primary research by distributing questionnaires to 140 medical doctors and pharmacists (74.3% response rate), which constituted the approach for quantitative analysis. Phone interviews were further conducted for qualitative analysis with 10 highly experienced healthcare professionals (over 10 years of experience). The author applied the positivism and interpretivism philosophies to analyse the questionnaire and phone interview findings respectively.

     
     
     
     

    Findings:

    Both groups of healthcare professionals were compared to determine their opinions on frequency of observed and reported ADRs, reasons for high underreporting rates, awareness of ADR reporting methods, guidelines and regulations as well as the NAFDAC regulatory body responsible for handling submitted ADR reports. A total of 104 out of 140 responded to the survey, of whom 53 (75.7%) were medical doctors and 51 (72.9%) were pharmacists. 34.0% of medical doctors who responded did not know how to report ADRs compared to just 5.9% of pharmacists who responded. In ascertaining familiar ADR reporting method, 39.0% of respondents selected yellow cards/ADR forms, 11.0% of respondents selected the ADR e-reporting form while 25.0% of respondents were familiar with both methods. 25.0% of respondents were unfamiliar with any of the methods for reporting ADRs in Nigeria. 36.0% of respondents admitted having reported an ADR within the past 12 months. The majority 57.0% of respondents indicated not to have reported an ADR in the past 12 months while 7.0% of respondents were unsure if they did. An overwhelming 90.0% of respondents opted for ADR reporting being made compulsory as a professional obligation towards pharmacovigilance.

    Analysis:

    Analysis showed that medical doctors and pharmacists have only an average knowledge and awareness of ADR reporting in Nigeria. They can correctly identify ADRs and the criteria for reporting but effective reporting remains a challenge. Pharmacists had better knowledge, awareness and experience over medical doctors regarding ADR reporting in Nigeria. However, despite overall poor attitudes to reporting ADRs, both groups exhibited a willingness to do better if proper continuous education and training is made available. NAFDAC performed poorly in raising awareness, providing training and encouraging better drug safety practices and pharmacovigilance. Very few healthcare professionals are aware of the guidelines or regulations governing the ADR reporting system in Nigeria. The authorities rarely acknowledge or follow up on reported ADRs which results in poor reporting rates. Factors varied among both groups as the challenges faced by medical doctors does not translate to the same challenge faced by pharmacists. However, both groups of HCPs agree that ADR reporting should be made a professional obligation to improve ADR reporting in Nigeria. Despite an overwhelming acceptance of the authors' recommendations, some opposed extra remunerations for every ADR reports made as it might distract from the ideal purpose of ADR reporting and pharmacovigilance- improving drug and patient safety in Nigeria.

    Conclusions:

    Factors ranging from indifference to ADR reporting, poor knowledge and accessibility of reporting methods, poor awareness of guidelines surrounding the reporting procedures are to great extent the same as observed from other studies in Nigeria and other countries. While few studies on ADR reporting in Nigeria compare multiple groups of healthcare professionals, this study demonstrates that pharmacists are more predisposed to favorable outcomes regarding ADR reporting than their medical doctor counterparts. Improving ADR reporting in Nigeria would greatly reduce the healthcare costs and mortality rates and further reduce the incidence of ADRs observed. As suggested by both groups of healthcare professionals, a review of regulations to make ADR reporting compulsory as a professional obligation towards patient safety bears great potential. The course content of the medical and pharmaceutical students should be reviewed to include modules on ADR reporting and tutorials on pharmacovigilance and drug safety practices prior to graduation. Health institutions should establish ADR departments headed by ADR specialists to improve reporting rates in Nigeria and foster liaison with the National Pharmacovigilance centers.


  • "Enhancing pharmacovigilance in Nigeria: Challenges faced by NAFDAC in monitoring of Adverse Drug Reactions in Nigeria." by Chinedum Odigbo

    Moyosore Oluwatoyosi OsokoNigeria, for a long have time been characterised by challenges in the medical sphere. This has given rise to increased mortality and morbidity rates in Nigeria. Apart from the challenges faced, there exists a low level of monitoring of adverse drug reactions. Drugs being authorised into the market are scarcely monitored to ascertain if there exist other side effects not observed in the clinical trials. Regulatory agency(NAFDAC) responsible for monitoring of drugs in the post-market authorisation period have not been effective in the dispensing of their duties which has contributed to the increased rate of mortality and morbidity in Nigeria.


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     Objectives:

    1. To determine if NAFDAC possesses the capability to monitor and address reported ADR cases.

    2. To identify the factors that hinder NAFDAC from effectively monitoring ADR in Nigeria.

    3. To proffer solutions that will help boost ADR monitoring by NAFDAC.

    Methodology:

    RESEARCH APPROACH: Quantitative
    RESEARCH METHODS: Descriptive research method.
    RESEARCH PHILOSOPHY: Positivism.
    PROBABILITY SAMPLING: Simple random sampling method.
    SAMPLE SIZE DETERMINATION: Cochran’s formula was adopted.
    METHODS OF DATA COLLECTION: Primary research was used.
    RESEARCH INSTRUMENT: Close-ended electronic survey questionnaire.
    VALIDITY OF THE RESEARCH INSTRUMENT: Face validity and content validity
    RELIABILITY OF THE RESEARCH INSTRUMENT: Cronbach’s alpha coefficient was used.
    METHOD OF DATA ANALYSIS: Statistical Package for Social Sciences using descriptive statistics.
    ACCESS & ETHICAL CONSIDERATION: Participants were given the free will to decide to participate in the study or not, were duly informed about keeping their identities hidden and information confidential.
     
    Findings:

    As revealed by the research findings, one of the challenges affecting NAFDAC’s effective monitoring of ADR is the inconsistent training of staff on latest developments in ADR monitoring. Not keeping staff abreast with recent developments in the monitoring of ADRs is a significant factor that hinders the effective practice of ADR monitoring by the regulatory agency. As a result, regular trainings where staff’s knowledge are updated with current trends with respect to ADR monitoring should be conducted. It is without doubt that ADR monitoring stems from the reporting of ADRs. One of the factors limiting NAFDAC’s ineffective monitoring of ADR is the reluctance of medical practitioners and consumers to report ADR cases. And the when ADR cases are not reported, the practice of monitoring cannot be carried out.
     
    Analysis:

    The analysis of this study have revealed that most NAFDAC staff understand the concept of ADR monitoring.This has provided the study with a solid foundation for answering its research questions because responses given by the study’s participants can be trusted due to their understanding of the study’s main subject matter – ADR monitoring. It was discovered from the analysis that monitoring of ADRs would impact positively on the safety of public health and that a positive relationship exists between ADR monitoring and reduction in ADR cases. These findings reveal the significant role ADR monitoring plays in safeguarding the public health of the people of a nation. In the health sector of every nation, it is advisable for ADR monitoring to be taken seriously due to the significant role it plays in protecting the strength of a nation.

    Conclusions:

    The researcher concludes that of a truth the Nigerian regulatory agency, NAFDAC has the capability to effectively monitor and address ADR issues but that attention should be given to the use of technological solutions in the carrying out of ADR monitoring practices as seen in Kenya. This would in turn increase the agency’s effectiveness in the monitoring of ADRs in the nation. Moreover, the staff revealed some other factors that hinder the effective monitoring of ADRs by NAFDAC. These factors include; poor and inconsistent training of staff, poor administration of the agency, corruption and conflict of interest, lack of qualified manpower, reluctance of most healthcare professionals to report ADR issues, and consumers who refuse to report ADR experiences after consumption of a drug.

  • "EXPLORATION OF THE IMPACT OF INFORMATION AND COMMUNICATION TECHNOLOGY DEVELOPMENT ON COMMUNITY PHARMACY PRACTICES IN NIGERIA (ETI-OSA, LAGOS)" by SALIU ADELEKE YUSUF

    PharmacyIntegration of ICT-based techniques into the practice of community pharmacy has reshaped the professional job functions of modern day community pharmacists as attention is being given in continuum to patient-oriented services. Issues such as medication error, undue waiting time, prescription problems to mention a few are being effectively addressed and managed courtesy of ICT-based techniques such as e-prescription, telecare, barcode scanning to etc. usage in the work station of community pharmacists. These techniques among others have also been observed and reported to reduce the workload of community pharmacists which in turn create more time to offer patient-focused services.

     


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     Objectives:

    The aim of the present work is to explore the practice of community pharmacy in Lagos state through the eyes of community pharmacists and their perception on the use of the novel information and communication technology ICT, and its effective implementation in the practice of community pharmacy in state and hence the Nigerian communities. Other objectives include:

    • Exploration of the professionalism, work practice and ethics of community pharmacist in Lagos state, Nigeria

    • Exploration of the observed non-adoption and hence ineffective usage of ICT-based techniques such as the use of computerized network in recording, storing and accessing patients’ health information; electronic prescription as well as telecare services by community pharmacists in the research study locality.

    • Identify the bottlenecks and hence barriers responsible for non-employment/ineffective use of ICT in the practice of community pharmacy which overshadowed the field in Nigeria.

    • Explore the importance of and how ICT-based techniques usage in the practice of community pharmacy would improve and thus benefit all stakeholders associated with the Nigerian healthcare system.

    • Proffer novel and insightful ideas and solutions that can lead to the effective adoption and full implementation of ICT techniques across various community pharmacies in Lagos state and thus improving the Nigeria health care system 

    Methodology:

    The present work was modelled on qualitative research pedagogy and relied on the use of deductive survey questions. The research study was conducted specifically in the selected locality of Eti-Osa, EtI-Osa Local government area within the Lagos State metropolis, Nigeria. This was facilitated through a conducted semi-structured interview that led to the generation of in-depth explanatory data obtained from a small sample of licensed and practicing community pharmacists (those in stand-alone stores) using the pre-drafted qualitative survey questions as research tool
     
    Findings:

    Based on the research findings obtained from semi-structured interviews conducted on licensed and practicing pharmacists in Eti Osa LGA, Lagos metropolis, it is found that information and communication technology just like how it always enhances and thus redefine professional functions in every work station, can also redefine community pharmacy practice in Nigeria. In the present research study area community pharmacists, which discharge their professional duties in a standalone pharmacy were well conversant with the concept of ICT application which is somehow lacking in the practice of community pharmacy in developing countries such as Nigeria,
     
    Analysis:

    For the present study, the research data from the respondents were analyzed through Deductive Thematic Analysis approach. This qualitative method of data analysis follows six models which include (1) Reading through transcribed text and establishing data correspondence with the research focus; (2) “Coding” of texts to bring out the salient points and similar response pattern from respondents; (3) Using the coded texts to generate a themes; (4) Reviewing the generated themes so as to offset data anomaly and research bias; (5) Renaming the themes as the case may be; and (6) Writing up a theme to aptly capture and project a particular research observation.

    Conclusions:

    The findings made shows the non-existent or usage of ICT-based techniques such as Electronic Prescription in the line of duty of community pharmacists strained these health professionals who had to deal with the enormous workload that comes with manual filling of medication prescriptions, while researchers including Afolabi and Oyebisi (2007) as well Leung and colleagues (2013) opined that the professional duties of community pharmacists in Nigeria do not measure up greatly as ICT-based techniques which would help offset the never ending problems of medication error were lacking. Consequently, community pharmacists in the present studies advocated for the introduction of such ICT based techniques into their work station and laid much emphasis on the need of real technical and professional training on the use of these ICT techniques which they regard as one of the key determinants that would make them to be flexible while discharging their professional functions, saving them a sizeable time that had been chunked and helping combat problems such as medication errors.

  • "The impacts of Drug Importation Regulation on Local Pharmaceutical manufacturers in Lagos Nigeria." by Osuchukwu Chisom Lawrence

    Mr. Osuchukwu Chisom LawrenceBefore the existence of drug manufacturing in the 1960s, the pharmaceutical industry in Nigeria were predominantly based on importation of large scale of pharmaceutical products. The early stage of drug manufacturing in Nigeria began in 1944 with May and Baker Nigeria PLC. Currently, there are more than 115 registered pharmaceutical manufacturers in Nigeria providing high quality medicinal products to Nigerians and West Africa. They have equally contributed positively to the growth of Nigeria economy. The pharmaceutical companies in Nigeria are in the business of manufacturing pharmaceutical dosage forms like analgesics, antimalarial, antibiotics, anti-retroviral, antacids, haematinics, vitamins and minerals, cough and cold remedies, anti-diarrheal, antihistamines anti-ulcer, antihypertensive, anti-diabetics etc. The above products can be found in registered hospitals, pharmacies, and distribution outlets in Nigeria. (Pharmapproach, 2019). Akiny 2013, in his research work on Counterfeit Drugs in Nigeria Reports that despite the numerous numbers of pharmaceutical companies present in Nigeria, only about 60 of them are in active manufacturing of pharmaceutical products in Nigeria.

     


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     Objectives:

    The study objectives are follows:

    - To identify the key regulations on drug importation and its impact on Local Manufacturing in Nigeria

    - Identify the impact (positive and/or negative) of foreign contract manufacturing on local drug manufacturing

    - Identify the key challenges faced by local drug manufacturers in Nigeria

    - Provide recommendations to improve the local drug manufacturing in Nigeria.

    Methodology:

    To determine the impacts of drug importation regulations on local pharmaceutical manufacturing in Lagos Nigeria, the author adopted a quantitative and qualitative research method by using questionnaire surveys and zoom meeting interviews. The survey was distributed electronically to the local pharmaceutical manufacturing industries in Lagos Nigeria, who are also key importers of drugs in Nigeria. They are the main research group and were asked to fill the survey through the cooperation and assistance of the union (PMGMAN) that made their contacts available to the author. The cooperation between the local pharmaceutical unions in Nigeria assisted the author in gathering the required information and data used for the statistical analysis. The questions asked was specifically meant to get the general perception of the key players in the Nigeria pharmaceutical industry. Most importantly, to determine the impacts of drug importation regulations on local pharmaceutical industry in Lagos Nigeria. Along the same lines to get the challenges and recommendation for the growth of the industry that have depended so much on CMOs from India and China for 70% of their drugs. The qualitative approach of this research was via zoom meeting interviews to understand personal experience of the local drug manufacture’s and importers who have been in the business for more than one decade.
     
    Findings:

    The thesis aims at evaluating the impacts of drug Importation regulation on local pharmaceutical manufacturers in Lagos Nigeria by carrying out a questionnaire-based surrey and zoom interviews for quantitative and qualitative analysis respectively. In achieving the objectives of the study, the knowledge, awareness, and drawbacks faced by the local pharmaceutical industry were appropriately considered in order to derive at effective recommendations to improve local drug manufacturing in Lagos Nigeria. Both groups (local drug manufacturers/importers) in the pharmaceutical industry were compared to derive at their perspective on the impacts of drug importation regulations on their business. A total of 77 out of the 117 participated actively in the survey, of whom they combine pharmaceutical importation and local pharmaceutical manufacturing. Interesting, 83% of the participants admitted that the importation regulations in Nigeria are outdated and ineffective/inconsistent and have impacted negatively to the growth of the industry. However, an overwhelmingly majority of the local drug manufactures/importers also attributed the frequent taxation from state and non-state regulators as a major draw backs to local drug manufacturing that have yielded to the 25% capacity production of the Nigeria local drug manufacturing.
     
    Analysis:

    As evidenced by the analysis, most of the local manufacturer’s combines local drug manufacturing with its importation for the sustenance of their business since it is more expensive to manufacture drugs than its importation in Nigeria. The local manufacturers, PSN and PMGMAN admitted that the inability of the government in providing the enabling environment for local pharmaceutical manufacturing is among the factor that have discouraged local manufacturing of drugs. In addition to this they admitted that government regulations like high taxes and complex drug regulations have negatively affected the industry.

    Conclusions:

    In concluding this research work and its analysis on the impacts of drug importation regulations on local pharmaceutical manufacturing in Nigeria and after reviewing relevant literatures on the topic within the Nigeria pharmaceutical industry, the author found the process very informative and needful in solving the problem associated with the poor performance of the local pharmaceutical industry that have yielded to the 25% production capacity of the industry. Finally, the growth of the pharmaceutical manufacturing industry depends on the intervention of the Federal Government of Nigeria in providing the infrastructure’s, funds, policies and regulations which remains the key catalyst for the development of the industry and reducing the dependency on CMOs chiefly from India.

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